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Hypnosis fMRI and Pain Perception

Schulz-Stübner, S., Krings, T., Meister, I. G., Rex, S., Thron, A., Rossaint, R. (2004). Clinical hypnosis modulates functional magnetic resonance imaging signal intensities and pain perception in a thermal stimulation paradigm. Regional Anesthesia and Pain Medicine, 29(6), 549-556

Our observations indicate that clinical hypnosis may prevent nociceptive inputs from reaching the higher cortical structures responsible for pain perception. Whether the effects of hypnosis can be explained by increased activation of the left anterior cingulate cortex and the basal ganglia as part of a possible inhibitory pathway on pain perception remains speculative given the limitations of our study design.