From Man’s Search for Meaning by Viktor Frankl,
… What matters, therefore, is not the meaning of life in general but rather the specific meaning of a person’s life at a given moment.
… Ultimately, man should not ask what the meaning of his life is, but rather he must recognize that it is he who is asked. In a word, each man is questioned by life; and he can only answer to life by answering for his own life;
… We must never forget that we may also find meaning in life even when confronted with a hopeless situation, when facing a fate that cannot be changed. For what then matters is to bear witness to the uniquely human potential at its best, which is to transform a personal tragedy into a triumph, to turn one’s predicament into a human achievement. When we are no longer able to change a situation — just think of an incurable disease such as inoperable cancer — we are challenged to change ourselves.